The Longest-Running Evolution Experiment

Kommentarer 

  1. Tom shiba

    Tom shiba

    2 timmar sedan

    would be funny if one day thes ebacteria became small animals with eyes

  2. Terry Caldwell

    Terry Caldwell

    3 timmar sedan

    The smartest ad integration

  3. chuck sch.

    chuck sch.

    6 timmar sedan

    Wow, this is real nice science, love it! Keep going with you works its really cool. :D

  4. pkr pdl

    pkr pdl

    12 timmar sedan

    Natural selection and competitive selection is also just a imaginative hypothesis not proved yet.

    • Crispr CAS9

      Crispr CAS9

      2 timmar sedan

      "not proved yet." Proof isn't a thing in science, science operates on evidence and degrees of confidence. And natural selection has more evidence than just about any other theory in science.

  5. pkr pdl

    pkr pdl

    13 timmar sedan

    This experiment support adaptation within same species. Not evolution. Can scientists evolve this bacteria into multi-cellular organism? That will be wonderful. No-one can do that. Darwin theory is just an observation. A hypothesis.

    • Crispr CAS9

      Crispr CAS9

      2 timmar sedan

      @pkr pdl Sorry, but I have no idea what it is you are trying to ask me here. Feel free to try again.

    • pkr pdl

      pkr pdl

      2 timmar sedan

      @Crispr CAS9 bacteria do have so short life span. What if this kind of experiment continues to evolve to higher genus and if possible family?

    • Crispr CAS9

      Crispr CAS9

      2 timmar sedan

      "This experiment support adaptation within same species. Not evolution" Evolution is the change in allele frequencies in a population over successive generations, which this definitely is. "Can scientists evolve this bacteria into multi-cellular organism?" Not with this experimental setup, but other experiments have produced multicellular bacteria.

  6. Matthew Salvatar

    Matthew Salvatar

    14 timmar sedan

    Wait, so if I get the ending there. Life shows a capacity to transcend entropy?

  7. Danish

    Danish

    17 timmar sedan

    When did Adam Ragusea start doin science content ?

  8. michaelsimkin

    michaelsimkin

    Dag sedan

    According to the evolution theory they were supposed to develop into a multicellular organism or something. And this is what we do not see.

    • Crispr CAS9

      Crispr CAS9

      21 timme sedan

      "According to the evolution theory they were supposed to develop into a multicellular organism or something." So you're saying you don't know anything about evolutionary theory? Fun.

  9. erikfinnegan

    erikfinnegan

    Dag sedan

    Veritasium FAKE for money: big experiment setup to pitch paper towels - microprint disclamer in the end says that experiment is "not representative". Not the the sort of statistical significance that I've grown used to wrt this channel. Oh, and you should always use recycled material or wash. There's always room for a couple kitchen cloths in the washer.

  10. David Kellen

    David Kellen

    Dag sedan

    I'm really concerned about how they handle bacteria... No gloves, just a slight "Touch" in the fire and "importante" the material and bacteria are being exposed to Open air...

  11. Tyray3P

    Tyray3P

    Dag sedan

    It's all well and good until the germs can transfer through xenonite

  12. Cedric Velarde

    Cedric Velarde

    Dag sedan

    1st gen e coli: we cant eat that its deadly! 1000000+ gen e coli: u wut m8?!

  13. A Real Life Dog

    A Real Life Dog

    Dag sedan

    Crematoriums are for organisms that are already dead... Those furnaces look more like something found at Dachau

  14. МАТЬ-РОССИЯ

    МАТЬ-РОССИЯ

    Dag sedan

    *how to create a supervirus*

  15. gyamlj

    gyamlj

    Dag sedan

    This is a highly controlled environment. Compare the competitive advantage of the newest and oldest colonies in a natural world where innumerable other factors weigh in to survival. It may very well be that the older organisms are better able to survive. This is analogous to selective breeding that creates an animal with desired characteristics but is otherwise less capable of overall survival compared to its ancestors. I'm afraid this teaches me nothing.

    • Crispr CAS9

      Crispr CAS9

      21 timme sedan

      "I'm afraid this teaches me nothing." Says more about you than the experiment, I think.

  16. Ashethorama

    Ashethorama

    2 dagar sedan

    Did anyone else notice the reference from the movie “The 13th Warrior” on the fridge? Timestamp 7:50 minute

  17. Seven Ligthson

    Seven Ligthson

    2 dagar sedan

    YES! Nothing out is not in and everything out is in ;-)) 1.5 (oo.000) is human program given by life = love = what you are in need of, who (do you) are (you)? I took my ABO once more!

  18. Christopher Inman

    Christopher Inman

    2 dagar sedan

    Queen Elizabeth I (of England) cooked a fruitcake for members of parliament to celebrate its opening. A bit was saved to be included in the next parliament's opening, etc. So now, when parliament begins its new season, the members are privileged to have a bit of cake cooked by Shakespeare's favorite monarch! [i have not fact-checked this because i don't want to find out if it is not true]

  19. maruftim

    maruftim

    2 dagar sedan

    Mad scientist fell into bacteria gacha hell...

  20. AJ T

    AJ T

    2 dagar sedan

    Is he referring to Confirmation Bias or is it something else?

  21. ZedCactus

    ZedCactus

    2 dagar sedan

    This episode was great! Really interesting.

  22. Lief Bamberg

    Lief Bamberg

    3 dagar sedan

    disappoinited that derek is now hawking that idea that greater bacterial spread is somehow dirtier, and that you should use disposible environment wrecking paper over washable cloths.

  23. WowZers

    WowZers

    3 dagar sedan

    Imagine being the chad bacteria to first eat the citrate

  24. Rodrigo Segura

    Rodrigo Segura

    3 dagar sedan

    42, ¿coincidence? I think not

  25. Frenchnostalgique

    Frenchnostalgique

    3 dagar sedan

    Prof Richard Lenski has the same accent as Rich Evans and it's throwing me off.

  26. Azurium

    Azurium

    3 dagar sedan

    Me seeing 1% selection first hand: "So that's what the aliens are doing to our universe and what the Great Filter could be."

    • Azurium

      Azurium

      3 dagar sedan

      Context: imagine that at 7:30 he's talking about intergalactic species expanding across the universe.

  27. Christian412 America

    Christian412 America

    3 dagar sedan

    The educated dumbasses still call it evolution. After 70000+ generations the bacteria is still producing bacteria. The bacteria has not produced anything but bacteria. Why is it so hard to get un biased conclusions? The only thing that has been observed is ADAPTATION not evolution.

    • Crispr CAS9

      Crispr CAS9

      3 dagar sedan

      "The educated dumbasses still call it evolution" Evolution is the change in allele frequencies in a population over successive generations, which this definitely is. "The bacteria has not produced anything but bacteria" If they produced something other than bacteria, it would disprove evolution. You understand that, right?

  28. SuperSonic Boom

    SuperSonic Boom

    3 dagar sedan

    Nah, if the flask breaks we become the solution to the experiment.

  29. Michael Kurek

    Michael Kurek

    3 dagar sedan

    It’s called mutation or adaptation. NOT EVOLUTION! The bacteria will always remain bacteria, just more resistant.

    • Crispr CAS9

      Crispr CAS9

      3 dagar sedan

      Evolution is the change in allele frequencies in a population over successive generations, which this definitely is.

  30. Guy Fox

    Guy Fox

    4 dagar sedan

    IT'S GOD! LOL

  31. Samaila Abdullahi

    Samaila Abdullahi

    4 dagar sedan

    I am forever grateful to Dr IGUDIA on SE-one who cured me from herpes with his herbal medication, you are so real and trusted.

  32. RD2564

    RD2564

    4 dagar sedan

    Beautiful video. Biosciences are a rich hunting ground for new videos.

  33. David Blank

    David Blank

    4 dagar sedan

    So...when do they turn into monkeys??? Can monkeys evolve into bacteria???

    • Crispr CAS9

      Crispr CAS9

      4 dagar sedan

      "So...when do they turn into monkeys" Based on evolutionary science, never. If you think evolution suggests otherwise, you don't understand evolution.

  34. DeadEndFrog

    DeadEndFrog

    4 dagar sedan

    well don't judge the Qu when they do this to us :^)

  35. lalit pal

    lalit pal

    5 dagar sedan

    I see you evolving from young youtuber :D

  36. wildstar2424242424

    wildstar2424242424

    5 dagar sedan

    A million bacterial monkeys typing on a million bacterial type-writers.... One of them finally wrote the opening to hamlet

  37. Mike Tacos

    Mike Tacos

    5 dagar sedan

    13:48 A couple more generations and they’ll be growing eyes and noses.

  38. Mike Tacos

    Mike Tacos

    5 dagar sedan

    Then someone breaks the glass.

  39. Chris Koll

    Chris Koll

    5 dagar sedan

    I'll bet you I can make a dog "evolve" so that it will CRAVE something that canines would NEVER consume if left to their own tastes(sp?)...

    • mwuaha

      mwuaha

      5 dagar sedan

      what?

  40. Truther

    Truther

    5 dagar sedan

    Are tests like this being done on viruses?

  41. FuriousGeezer

    FuriousGeezer

    6 dagar sedan

    So what you are saying is, after 75,000 generations, it's just better bacteria, but in the same amount of generations we went from monkey to man? Why didn't it macro evolve?

    • FuriousGeezer

      FuriousGeezer

      5 dagar sedan

      @Crispr CAS9 fair enough! I am still seeing no evidence of macro evolution, but that timeline sure makes it look like more of a possibility. My timeline was clearly off

    • Crispr CAS9

      Crispr CAS9

      5 dagar sedan

      @FuriousGeezer "it's a long time from bacteria to monkey" Monkeys are not descended from bacteria. "We get what a billion or so years?" 3.5 billion from first life to complex life, another 100 million to get on land, another 150 million for mammals, another 100 million for primates, another 50 for humans. Approximately.

    • FuriousGeezer

      FuriousGeezer

      5 dagar sedan

      @Crispr CAS9 Both are human though, yes. I poorly worded it.

    • FuriousGeezer

      FuriousGeezer

      5 dagar sedan

      @Crispr CAS9 it's a long time from bacteria to monkey and again to man. Not sure there is time for that🤷🏼‍♂️. We get what a billion or so years?

    • Crispr CAS9

      Crispr CAS9

      5 dagar sedan

      In the same number of generations, our ancestors went from Homo erectus to Homo sapiens. Both of those are humans.

  42. Neiley

    Neiley

    6 dagar sedan

    so how long til one of the containers crawls off? :P

  43. sf

    sf

    6 dagar sedan

    using the same needle for different flask samples???!!

  44. Bangs Cutter

    Bangs Cutter

    6 dagar sedan

    The human scale equivalent of this would be alien abduction encounters, where aliens continuously sample humans as they observe our evolution.

  45. Brad Shymon

    Brad Shymon

    6 dagar sedan

    Shouldn't forget all the generations of students who evolved the professor's knowledge and status! 🧐

  46. realitycheck2001

    realitycheck2001

    6 dagar sedan

    Wait. She wasn’t wearing gloves. Am I missing something?

  47. Gary CLark

    Gary CLark

    6 dagar sedan

    Ok thats stretch of a comparison. The mutations of a one cell bacterium are quite different than the mutations that would have to occur for an ape like creature to transform into what man is today. I don't care how many million years you tack on to it.

    • Crispr CAS9

      Crispr CAS9

      2 timmar sedan

      @Gary CLark "definition of a species is the ability to reproduce viable offspring" That is not a definition of species at all, and certainly not the way the word is used in biological science. "I would argue there is proof in science or rahter evidence if you want to call that" Since proof and evidence are not synonyms, this is not a question of preference. One is correct, the other isn't. There is no proof in science. "organized randomly through mutation in a way to create vision." The organization is by selection, which is non-random. Mutations just produce the variation that selection can act on. "how do we know it's random" Because we know how mutations work, to a reasonable degree of accuracy. "Could it not be hormonal?" Hormonal differences can cause differences in fitness, but what causes the differences in hormones? To the best of my knowledge, all differences in hormones are either differences in genetics or differences in environment acting on genetics. And here we are talking about a subset of the population with a differential hormonal response when exposed to the same environment as the rest of the population, so it can *only* be the underlying genetics that explains it. "or that the organism sensing something is changing" Let's say this, or any of the rest of what you suggest happens: the question is 'how is it happening in *some* members of the population and not others?' Is there an answer other than genetics available?

    • Gary CLark

      Gary CLark

      18 timmar sedan

      @Crispr CAS9 definition of a species is the ability to reproduce viable offspring, while a human definition which all things pertaining Evolution are, I think you would agree it's a very good definition considering if you can't reproduce you can't propagate your own kind. Mules for example are not a species because they cannot reproduce. They are a hybrid cross and are sterile. I would argue there is proof in science or rahter evidence if you want to call that, otherwise why push forward research when you can't prove anything. Novel organs do have tissues and nerves which are co-opted in other ways not pertaining to those organs, but this is deductive reasoning to assume that because they exist in othwr forms does not mean they can be organized randomly through mutation in a way to create vision. Your last part is what is hard for me to wrap my brain around, so if a random, neutral, mutation becomes important as the conditions surrounding the organizism changes how do we know it's random. Could it not be hormonal? or that the organism sensing something is changing in the environment and so chemical reactions in the brain induce changes in that organisms features to adapt to new environments. I don't know if that's even a thing. But it's intriguing.

    • Crispr CAS9

      Crispr CAS9

      22 timmar sedan

      @Gary CLark "Do mutations cause evolution." This is poorly phrased. Mutations *are* evolution (for bacteria, at least), in the strict sense, as they are changes in allele frequencies in a population over successive generations. They can also cause selection, another mechanism of evolution. "We have proof " There is never proof in science. " but we have zero accounts that I am aware of on one species evolving into another." This is also poorly phrased. Species are human labels, populations become different species when humans decide they are. But evolution can result in an accumulation of differences between two populations, or between one population and its ancestral population, such that humans are likely to determine them to be different species. "What evidence do we have that mutations for example created an eye or a wing?" Eyes are pigments and nerves in a particular arrangement. Both the pigments and the nerves are useful without vision, and can be co-opted into a visual system. Wings are just weird limbs. Neither eyes nor wings require, per se, novel proteins, only novel regulation. And we have plenty of evidence of mutation generating novel regulation. "Its quite another for a complex organism to evolve into an even more complex organism." I agree in part. Initial increases in complexity would be contingent and unlikely, but that is actually consistent with the history of life on earth, with the first 3.5 billion years of evolution producing very little in the way of increased complexity. However, past this initial step, most differences between organisms are regulatory novelty, not protein novelty. "Most mutations are neutral, bad ones are rooted out and, good mutations rarely make it to the next generation." Yes but, yes, and no. Good mutations frequently make it to the next generation, but more importantly most neutral mutations are only neutral in the current context of the organism. A mutation causing slightly thicker hair in an animal in a temperate climate would be neutral (adaptive in the winter, deleterious in the summer). But if the climate changes, or the population expands to different climates, then that initially neutral variant is suddenly non-neutral. This type of contingent selection on previously neutral variation is extremely important in morphological evolution.

    • Gary CLark

      Gary CLark

      Dag sedan

      @Crispr CAS9 I guess for me it boils down to mutations. Do mutations cause evolution. Is there any other mechanism that brings about evolution. We have proof of inherent changes among species that help them to become more suitable in their environment, but we have zero accounts that I am aware of on one species evolving into another. What evidence do we have that mutations for example created an eye or a wing? Changed a flipper to an arm. It is one thing for a bacteria or a virus to change the way it defends itself. Its quite another for a complex organism to evolve into an even more complex organism. Most mutations are neutral, bad ones are rooted out and, good mutations rarely make it to the next generation. I believe that mutations can and do add value and variety to individual species, but I see no evidence of mutations evolving from one species to another. I guess that's my point, it all seems mute if there is no smoking gun, they have been searching for it for 150 years, yet no evidence. What bugs me the most is how religious scientists have become on the subject of evolution. They accuse creationists of only relying on faith yet much if what they proport to believe as true has about as much evidence. I don't understand the us against them mentally that has cropped up in science lately,(or has it always been the case) the same with climate change, this pandemic. It feels like science is being exploited for political gain. It's losing it purity.

    • Crispr CAS9

      Crispr CAS9

      3 dagar sedan

      ​@Gary CLark "Many species remain virtually unchanged for millions of years, then suddenly disappear to be replaced by a quite different, but related, form." Let's say that was completely true for every group. How would it be relevant to anything in my prior comments, specifically? Does it provide a metric for 'flourishing'? Does is it address the greater fitness of chimpanzees in their environment? The nature of scientific theories and laws? No to all. Nor does it present a mechanism for 'crafting' organisms. Does it support any of your later statements that do address some of these? No again. So why bring it up? Most groups don't fit that pattern, by the way. "Moreover, most major groups of animals appear abruptly in the fossil record" First, same initial commentary as above. Anyway: If you mean in the Cambrian, then that is partially true, although we are starting to find some organisms from the Ediacaran. That's still enough to show the evolution of all vertebrates, for instance. " fully formed" We never expect to find any 'half-formed' organisms, that's not how evolution works. "and with no fossils yet discovered that form a transition from their parent group." This isn't a problem for human evolution. The fossil record is fairly extensive. "This pattern is contrary to what would be expected from Darwinian evolution." Darwinian evolution only makes predictions on what should be found in the fossil record in the sense of predicting the chronological order of specimens that might be found, not what should be found in the actual rocks. For instance, if an initial radiation occurs rapidly in a small population, especially for small and soft bodied animals, it is unlikely that we would find many fossils at all. But if we DID find some, then they should occur in a particular pattern. Failure to find the Ediacaran soft-bodied ancestors of vertebrates, for instance, is neither consistent with nor contrary to evolution. Finding a rabbit mixed in with the Ediacaran would definitely be contrary to evolution. "Genetics has punched more holes in it lately." Genetics provided a stronger support for evolution than any single field has ever provided to any single theory in the history of science. "and not to rely on random chance mutations to explain" Mutation is a known process that can do what needs to be explained. That certainly doesn't mean it is impossible for some other process to be involved, but until it is presented, mutation will continue to be the best explanation currently available. "I am however enjoying this conversation." I've talked to a few people under this video, you've been the best so far.

  48. Chris M

    Chris M

    6 dagar sedan

    Still waiting. When did bacteria have gain in function/information and become a dog? Nowhere in the world does that occur. Besides all fossils having soft cell tissues in them is clear and abundant evidence evolution does not occur. There are not enough trillions and quadrillions of years for "mutations" required to have gained in function as soft cell tissues have how long a life? Your experiment does nothing but proves the existence of a "pre-programmed will to survive" or immunity as your body posses. Mankind did not evolve from apes or will they evolve into something other than humans. Transitional fossils? Where?

    • Crispr CAS9

      Crispr CAS9

      6 dagar sedan

      @Chris M "That is the events evolution proposes." No, it isn't.

    • Chris M

      Chris M

      6 dagar sedan

      @Crispr CAS9 That is the events evolution proposes.

    • Crispr CAS9

      Crispr CAS9

      6 dagar sedan

      "When did bacteria [...] become a dog?" If bacteria became dogs, that would disprove evolution. You understand that, right?

  49. Vinícius M

    Vinícius M

    6 dagar sedan

    E.Colocaust :(

  50. Chris Carriere

    Chris Carriere

    6 dagar sedan

    Isn't it possible to try and make bacteria evolve into eating stuff we treat as garbage ? Like idk all the "bad" gases etc. Could solve a lot of problems

  51. Stephanie Hyatt

    Stephanie Hyatt

    6 dagar sedan

    I hate to mention this, but unless you are composting your paper towels, use re-usable microfiber cloths that you can throw in the washer. I use them occasionally, but rarely for cleaning.

  52. Ismael Abufon

    Ismael Abufon

    7 dagar sedan

    12:31 ... I 100% read Gattaca haha

  53. Ismael Abufon

    Ismael Abufon

    7 dagar sedan

    The lucky 1% gets to reproduce..... like the super rich haha

  54. Peter Smoyer

    Peter Smoyer

    7 dagar sedan

    Space itself is the thing that is evolving. All the matter, energy and radiation that exists in the universe at one time fit into something the size of a soccer ball or perhaps a football stadium. It all came from space. It is all here to benefit space. Space would not be as expansive as it is without the matter and energy it created in less than one second.

  55. Antisocial Atheist

    Antisocial Atheist

    7 dagar sedan

    I could sit down and talk with that guy for days lol. Very interesting and informative. If I could meet him I'd have to thank him for his work

  56. Plum Amazing

    Plum Amazing

    7 dagar sedan

    The best example of this kind of research is a really old story by the author of 'Game of Thrones' George R.R Martin. It's one of his best. It's a short story called 'Sandkings'. There is the book on youtube. Also the outerlimits video also on youtube. Sorry I can't put up links you'll have to search youtube. Very scary one to read. I suspect you will like it. muhahaha

  57. Falsimer

    Falsimer

    7 dagar sedan

    When the music kicked in I got a wave of nostalgia. I saw your source, but what it reminded me of was the Majora's Mask Milk Bar Theme. The most simultaneously upbeat and sorrowful music I can think of right now. Only the first 5 or so notes of your music matched the Theme, but it was enough to spark my memory.

  58. Benjamin Márkus

    Benjamin Márkus

    7 dagar sedan

    that transfer process was suprisingly lax! :o i would’ve thought you’d want to do this under suction cabinet with purified atmosphere and such.

  59. sokin jon

    sokin jon

    7 dagar sedan

    “33 years ago, even on weekends ever since ..” Bacteria are annoyingly hard workers.

  60. mbbs2008

    mbbs2008

    7 dagar sedan

    Perhaps this is adaptability? Quiet possible that bacteria have different (higher) adaptability potential then higher animals?. The bacteria still remained "bacteria" at the end, even after 30 years relentless "experimentation", and did no really "evolve" into a new species? Am I missing something?

  61. mike powers

    mike powers

    8 dagar sedan

    This is a great experiment in micro evolution and also acts as an experiment in macro evolution as well, if macro evolution were possible there would be signs after 70k generations but, that is not the case. No matter how resilient or mutated these samples are they are still E. coli bacteria and not E. coli/??? Or something completely different.

    • sokin jon

      sokin jon

      7 dagar sedan

      stove, etc. It's WAY too wasteful to use paper towels! SHAME on you, for promoting such wastefulness!!

  62. jonnyjazzz

    jonnyjazzz

    8 dagar sedan

    So this is what Chase is doing these days. Decided he liked the red-head look, too.

  63. Emmanuel N

    Emmanuel N

    8 dagar sedan

    Evolution really isn't true devolution or decay is much more realistic

  64. Tom James

    Tom James

    8 dagar sedan

    Where are the damn gloves?

  65. Máté Ócsai

    Máté Ócsai

    8 dagar sedan

    This video was amazing. I was hooked from the beginning.

  66. Roberto Serrini • The Travelclast

    Roberto Serrini • The Travelclast

    8 dagar sedan

    bounty blew my mind

  67. Ad Lakerveld

    Ad Lakerveld

    8 dagar sedan

    It seems dangerous to me learning bacteria to survive antibiotics

  68. X17

    X17

    8 dagar sedan

    This is a perfect plot for a disaster movie

  69. X17

    X17

    8 dagar sedan

    why 42 though?

  70. betaneptune

    betaneptune

    8 dagar sedan

    This is the great experiment Richard Dawkins describes in his book _The Greatest Show on Earth: The Evidence for Evolution_!

  71. Ezgi Umut

    Ezgi Umut

    8 dagar sedan

    As far as I understand the environment in this experiment is strictly controlled with constant and optimal temperature and nutritional content. There are no other species present. E.coli to grow faster in such an environment is most likely explained by the fact that these bacteria evolve to spend less energy and time to adapt to different temperatures, nutritional shortages (ex. storing carbohydrates), and competing with other species, allowing them to concentrate all metabolic activity on growth and reproduction. Thus, the "constant improvement" proposed by the researcher is questionable. This is probably not an improvement, it is only an action of increasing the activity of only one vital metabolic function (growth by using glucose) at the expense of others (adaptation to temperature, nutritional shortage, competition, etc.).

    • Crispr CAS9

      Crispr CAS9

      6 dagar sedan

      @Ezgi Umut "My comment is not a claim" Yes it is. You claimed that something was the most likely explanation, you must support this. You've also made a collection of claims in your new comment, and provided support for none of them. You're just making stuff up, no one cares.

    • Ezgi Umut

      Ezgi Umut

      6 dagar sedan

      @Crispr CAS9 My comment is not a claim, rather a necessary discussion before accepting that this experiment provides evidence to "continuous improvement" in a stable environment. I consider that it should be called continuous adaptation to the experiment's growth medium. The first generation E.coli of this experiment comes from the real world where it spent significant energy to preserve membrane potential to the changing electrolyte concentrations of its habitat, to adapt to temperature changes and nutritional content as well as producing multiple enzymes to produce energy from many non-glucose substrates. The hospitable and stable environment provided in this experiment is expected to result in selective atrophy of the aforementioned metabolic features of the bacterium that it gained to survive harsh living conditions; allowing more energy to be spent on growth and reproduction rather than metabolic defensive buffers, competition, etc. The researcher has to disprove this interpretation before concluding that continuous improvement takes place even in stable conditions. These bacteria are still adapting to this new friendly habitat (no fluctuations in sodium, phosphate, potassium, magnesium, citrate, ammonium concentrations, temperature, nutrition ) even if it has been going on for 30 years (which is not a long time) especially considering that it is markedly different from what the bacteria have evolved in millions of years. The atrophy of previously essential functions with environmental change has been described in many species even in vertebrates in Galapagos.

    • Crispr CAS9

      Crispr CAS9

      8 dagar sedan

      @Ezgi Umut " It is more likely that the outcome (growth rate) is better not because of progress, but rather from the atrophy of other metabolic functions that are necessary for life in the real world" This is your claim, present your evidence to support it.

    • Ezgi Umut

      Ezgi Umut

      8 dagar sedan

      @Crispr CAS9 the ability to grow without glucose (ex. metabolizing citrate) is a different discussion that takes place during the video. However, the main topic of interest that the researcher emphasizes at the conclusion is the constant improvement of the growth rate which concerns the bacteria incubated at the standard DM25 liquid medium (10% glucose). It is more likely that the outcome (growth rate) is better not because of progress, but rather from the atrophy of other metabolic functions that are necessary for life in the real world, that have become obsolete in this experiment method.

    • Crispr CAS9

      Crispr CAS9

      8 dagar sedan

      "it is only an action of increasing the activity of only one vital metabolic function (growth by using glucose)" The interesting finding is that are able to grow in the complete absence of glucose. Are you sure you watched the video?

  72. hoiy vinosa

    hoiy vinosa

    8 dagar sedan

    “33 years ago, even on weekends ever since ..” Bacteria are annoyingly hard workers.

  73. Blue Five

    Blue Five

    8 dagar sedan

    I'm put in mind of 'The Outer Limits' episode 'Wolf 359'.

  74. Soapy's Thoughts

    Soapy's Thoughts

    8 dagar sedan

    This reminds me of Primer

  75. Yout Funny

    Yout Funny

    8 dagar sedan

    Evolution is Adaptation Adaptability

    • hoiy vinosa

      hoiy vinosa

      8 dagar sedan

      i just love the hippie labcoat at 11.50 :-) ....sadly not gonna happen in my lab :-(

  76. Mary Ann Bittle

    Mary Ann Bittle

    9 dagar sedan

    Paper towels? Um, NO. Dish cloths, hand towels, sponges, all can be - get this - *WASHED* to sanitize them. No need, at ALL, to waste trees in order to wipe down the counter, stove, etc. It's WAY too wasteful to use paper towels! _SHAME on you,_ for promoting such wastefulness!!

  77. Robe005

    Robe005

    9 dagar sedan

    Damn, the ThermoFisher ad was awesome. Don't know what it was but the music and video were very satisfying:)

  78. Fred Bach

    Fred Bach

    9 dagar sedan

    No we're not viewing evolution as it happens. You are describing 'minor evolution' which is an adaptation to environment. It's still the same bug. It hasn't turned into another kind of bacteria. And the corn is still corn. Major evolution would result in a different bacterium or a different plant. I wish you evolutionists would stop lying to us. Stop using the smoke screen of minor evolution to prove that major evolution is a fact.

    • Crispr CAS9

      Crispr CAS9

      8 dagar sedan

      ​@Fred Bach "That was a library addition using Crisper " I don't know which experiment you're talking about, but it isn't any of the ones featured in this video. "Let me know when it turns into something that is not an E-coli." 'E coli' is a species designation, and species designations are human labels for human abstractions of populations. A sub population of E coli is no longer E coli when humans decide it, and by the ecotype conception of species delimitation the Ara-3 strain is already a new species. "Does the citrate ability come via the Rogues' Gallery or from elsewhere in the genome?" The citrate ability comes from a novel mutation, as confirmed by genomic sequencing of the ancestral and descendant strains. " If the latter, what will happen if you took the citrate away for 75000 generations? Might it lose its ability to handle citrate? " Sounds like you just suggested it can't be evolution if *more* evolution happens afterwards. I hope that isn't what you intended, since that would be silly.

    • Fred Bach

      Fred Bach

      8 dagar sedan

      @Crispr CAS9 the bugs were given a Rogues gallery of what compounds to be immune to. For instance the square carbon ring in penicillin family drugs. That was a library addition using Crisper.... rather than a genetic mutation. Your username comes from that process. It's still an E-coli with a bigger library and a genetic variation. This ability is given to most lifeforms. Let me know when it turns into something that is not an E-coli. Does the citrate ability come via the Rogues' Gallery or from elsewhere in the genome? If the latter, what will happen if you took the citrate away for 75000 generations? Might it lose its ability to handle citrate? This reminds me of the moths in England that turned from a light shade to a dark shade and back to light again when the air pollution was cleaned up. I know you will attribute that to preditors. You actually need to do the other half of the experiment and put the new bug in an old environment for 75000 generations and see what it gains and loses.

    • Null Pointer

      Null Pointer

      9 dagar sedan

      lots of small changes eventually make large changes...

    • Crispr CAS9

      Crispr CAS9

      9 dagar sedan

      "No we're not viewing evolution as it happens." Evolution is the change in allele frequencies in a population over successive generations, which this definitely is. "It's still the same bug." It isn't the same, the descendant can use citrate as a sole carbon source, which the ancestor could not. They have identified the mutations responsible, which were not present in the ancestor. It is demonstrably different. "It hasn't turned into another kind of bacteria. " 'Kind' is a nonsense word without any scientific validity. "Major evolution would result in a different bacterium" Then mission accomplished, as explained above. "or a different plant." If any of the descendants of bacteria were plants, that would disprove evolution. Asking as evidence for a thing something that would actually disprove that thing is a fairly clear indication you don't understand the subject in the first place.

  79. Oogie Padoogie

    Oogie Padoogie

    9 dagar sedan

    And in 30 more years (equivalent to 3 million years from the start), still nothing cool happened. Yawn.

  80. Fred Leonard

    Fred Leonard

    9 dagar sedan

    Time for flask beer pong?

  81. patricio patricio

    patricio patricio

    9 dagar sedan

    when you touch the elbow for said hi don't keep social distance needed for prevent covid

  82. Adnan haider

    Adnan haider

    9 dagar sedan

    New Hollywood movie plot, Planet of the Bacteria.

    • Polaris Raven

      Polaris Raven

      8 dagar sedan

      So, as opposed to a Grey Goo scenario (Out of control Nano-Bot Replicators), this would be a Green Goo scenario?

  83. random black hole

    random black hole

    9 dagar sedan

    So "life finds a way" even if it doesn't need to?

  84. Jorjon Jorjon

    Jorjon Jorjon

    9 dagar sedan

    Imagine if we are just an experiment inside an alien race flask, and we die because otherwise the experiment would become unmanageable.

  85. LoBoToM81

    LoBoToM81

    10 dagar sedan

    That was interesting.

  86. Scott Pike

    Scott Pike

    10 dagar sedan

    33 years and it’s still bacteria.

    • Random Dude

      Random Dude

      10 dagar sedan

      Just as evolution predicts.

  87. avadhut patil

    avadhut patil

    10 dagar sedan

    Everyone gangsta until bacteria evolve to have collective consciousness

  88. tarkaras

    tarkaras

    10 dagar sedan

    i just love the hippie labcoat at 11.50 :-) ....sadly not gonna happen in my lab :-(

    • miko foin

      miko foin

      10 dagar sedan

      millennia of “hominid” evolution? So how long did it take to get to “hominid” again? Would you mind taking me through that process, even theoretically, step by step? I’m very

  89. Mohammad Hasanain

    Mohammad Hasanain

    10 dagar sedan

    Tell me when the bacteria becomes a fish🤫

    • Crispr CAS9

      Crispr CAS9

      8 dagar sedan

      @Mohammad Hasanain "ok so you flipped to racism" Excuse me? That's a substantial accusation. Either support it or retract it. " I am a native speaker" Then the educational system has failed you. "and you judge me by my name" I judged you by your obvious inability to communicate in English. I had given you the benefit of the doubt that you were able to at least communicate in some other language. If you claim you're just incoherent generally, I'll take your word for it. When you've learned how words work and what a reasonable number of them mean, feel free to revisit this conversation and try again.

    • Mohammad Hasanain

      Mohammad Hasanain

      8 dagar sedan

      @Crispr CAS9 ok so you flipped to racism what would you do if I was in your county just god knows. All the things you talked about are things I can feel their influence but I can't feel the influence of the precious evolution. write what ever you want now, I will not answer you because I am a native speaker and you judge me by my name "science guy"

    • Crispr CAS9

      Crispr CAS9

      8 dagar sedan

      @Mohammad Hasanain "it's clear that you don't understand what am I saying" Given the fact that I am a native speaker of the language we're using, and I'm guessing you are not, I'd say that it is *much* more likely the problem is that *you* don't understand what I am saying. "so just answer this question, when was there any proof and I mean proof on evolution" Same time as there was proof of gravity: Never. There is no proof in science. If you deny evolution because there is no 'proof' then you must also deny gravity, electricity, the existence of microbes, and the reality of your own mind. Because you can't 'prove' any of them.

    • Mohammad Hasanain

      Mohammad Hasanain

      8 dagar sedan

      @Crispr CAS9 it's clear that you don't understand what am I saying or don't want to so just answer this question, when was there any proof and I mean proof on evolution and something transforming to something else like an ape or fish caroling out of the see 🤷🏽‍♂️

    • Crispr CAS9

      Crispr CAS9

      8 dagar sedan

      @Mohammad Hasanain "so science doesn't work on proof is that correct?" Yes. "If it is you're talking about a new science you invented" No. "and if you said "observed " an observation is enough proof for such a thing" An observation isn't proof. It is a data point that increases confidence. "where was it observed can you tell me?" PMC3277146 & PMC4380822, and others. "What I meant when I talked about the experiment was that it didn't happen in this experiment while it was this long, when can it happen?" Here's your logic, spot the error: "I just flipped a coin 5 times and didn't roll a six, therefore rolling a six with a fair die is impossible!" "So if I told you that I'm confident the moon is made of cheese" I'd be curious as to what statistical analysis you based that on, but strongly suspect you just didn't understand what I mean by 'confidence'. I'm using a statistical definition, not a common one.

  90. Psychentist

    Psychentist

    10 dagar sedan

    Love the turbulent flow Tshirt. LOL. This little feud is hilarious and I'm here for it.

  91. Larry Panozzo

    Larry Panozzo

    10 dagar sedan

    Generation 69,000: E. Coli have spelled out the words, “Let us out.”

  92. kolim jone

    kolim jone

    10 dagar sedan

    I would love to sit in the lectures of this professor. It is so pleasant to hear him explain!

  93. isaiah

    isaiah

    10 dagar sedan

    Lol, evolution isn’t real. There settled

    • Null Pointer

      Null Pointer

      9 dagar sedan

      lol, nobody of any relevance cares about your opinion.

  94. avitarmageddon

    avitarmageddon

    10 dagar sedan

    Let's hope those bacterium are not harmful to life around them when they escape. I'm not qualified to know whether they represent a danger or not but I do know that no containment protocols are 100% guaranteed, never can be.

    • Heinrich Himla

      Heinrich Himla

      8 dagar sedan

      i feel as if they wont survive well in the wild considering they're evolving in extremely favourable conditions for them

  95. Texas Ray

    Texas Ray

    11 dagar sedan

    What kind of idiots want to breed bacteria that are immune to antibiotics?

  96. Eren JAEGER

    Eren JAEGER

    11 dagar sedan

    I wonder if it’s possible for a mutation to arise where it produces an antibiotic that it is immune to but the other members of the population aren’t. It would probably require a long chain of silent mutations to occur in a very specific way and the resistance ability would have to evolve shortly before the antibiotic ability otherwise it may be too prevalent in the population

  97. Classic Riki

    Classic Riki

    11 dagar sedan

    This is extremely interesting, brilliant video all around. Something very disturbing about watching these bacteria evolve rapidly and seeing the rate explained compared to earth 🌍 while having seen them wearing masks due to Covid

  98. Micro Scale

    Micro Scale

    11 dagar sedan

    Can anyone please explain why he used fluorescent powder and uv torch? Please please please🙏🙏🙏🙏🙄

  99. Dylan Birrer

    Dylan Birrer

    11 dagar sedan

    absolute champ, this video is exactly what I need for the biology assessment I'm doing, there's so much useful information and you made me think about what I'm writing in a different light as well.

  100. Strange Velocity

    Strange Velocity

    11 dagar sedan

    0:59 Before I watch this video again.. Where can I get that t shirt? :O

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